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Psychopathology and Clinical Phenomenology

Vol. 30: Issue 3 - September 2024

Disorganization in early psychosis: clinical considerations

Disorganization in early psychosis

Authors

Key words: Disorganization, Clinical High Risk, Ultra High Risk, early psychosis, psychopathology, neurobiology
Publication Date: 2024-10-31

Abstract

In the last two decades, the resurgence of the “late neurodevelopment” hypothesis of psychosis has brought into focus Kahlbaum’s and Hecker’s clinical reports of adolescents who, as a result of a loss of psychic energy, showed a rapidly progressive cognitive impairment leading to functional and behavioral disorganization. In line with their psychopathological descriptions of hebephrenia and heboidophrenia, disorganization could represent a core clinical dimension of early psychosis, especially during its prodromal stages (such as in people with ARMS) and during adolescence. Although under-investigated, disorganized features seem to be associated with early neurobiological alterations, functioning decline, and poorer outcomes and prognosis. Greater clinical attention on disorganization in young help-seeking individuals from researchers and clinicians is thus needed. This paper first summarized past conceptualization of heboidophrenia and hebephrenia as developmental illnesses. We then discussed recent clinical and neurobiological findings on disorganization in individuals with early psychosis, highlighting its prognostic significance.

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Authors

Arianna Biancalani - Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University di Bologna, Bologna, Italy

Michele Occhionero - Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University di Bologna, Bologna, Italy

Lorenzo Pelizza - Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University di Bologna, Bologna, Italy

How to Cite
[1]
Biancalani, A., Occhionero, M. and Pelizza, L. 2024. Disorganization in early psychosis: clinical considerations: Disorganization in early psychosis. Journal of Psychopathology. 30, 3 (Oct. 2024). DOI:https://doi.org/10.36148/2284-0249-N430.
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